This is a railroad post office franked postcard. The mark reads “BRISTOL & CHATTANOOGA TR 4 JUL 11 1917 R.P.O.”
It was printed by Curt Teich of Chicago and published by The Novelty Store in Morristown.
If this is looking west, then the old Kingmyer Hotel is up there somewhere on the right.
Oh, and I hope Miss Sarah Stonecypher of Limestone knew who “Guess Who?” was…